Betamethasone 17-valerate

CAS No. 2152-44-5

Betamethasone 17-valerate( Betamethasone Valerate | Betoid | Valison | 9α-Fluo | Valisone | Bedermin )

Catalog No. M13436 CAS No. 2152-44-5

Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 41 In Stock
50MG 61 In Stock
100MG 91 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Betamethasone 17-valerate
  • Note
    Research use only, not for human use.
  • Brief Description
    Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
  • Description
    Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.(In Vivo):Betamethasone valerate (10 mg; 5 minutes; applied to the irritated site with a micro spatula) ointment inhibits about 50% of the ear edema without thymus atrophy.Betamethasone-17-valerate ointment (50 mg) inhibits homologous passive cutaneous anaphylaxis.
  • In Vitro
    ——
  • In Vivo
    Betamethasone valerate (10 mg; 5 minutes; applied to the irritated site with a micro spatula) ointment inhibits about 50% of the ear edema without thymus atrophy.Betamethasone-17-valerate ointment (50 mg) inhibits homologous passive cutaneous anaphylaxis. Animal Model:Female Sprague-Dawley rats weighing 60-70 g (croton oil edema experiment)Dosage:10 mg Administration:Applied to the irritated site with a micro spatula; 5 minutes Result:Inhibited about 50% of the ear edema without thymus atrophy.
  • Synonyms
    Betamethasone Valerate | Betoid | Valison | 9α-Fluo | Valisone | Bedermin
  • Pathway
    Endocrinology/Hormones
  • Target
    GR
  • Recptor
    Glucocorticoid Receptor
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    2152-44-5
  • Formula Weight
    476.59
  • Molecular Formula
    C27H37FO6
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 58 mg/mL (121.7 mM); DMSO: 95 mg/mL (199.33 mM)
  • SMILES
    O=C1C=C[C@@]2([C@]3([C@H](C[C@@]4([C@](OC(CCCC)=O)([C@H](C[C@]4([C@@]3(CCC2=C1)[H])[H])C)C(CO)=O)C)O)F)C
  • Chemical Name
    (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ortonne JP, et al. J Eur Acad Dermatol Venereol. 2014 Sep;28(9):1226-34.
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